—  Prior Art Search & Analysis

Biological Sequence Search

Our Biological Sequence Search uncovers even the complex sequences buried deep in patent and non-patent literature.

It is built for the work done by Fortune 500 companies and well-known research laboratories developing antibodies, primers, and therapeutics such as peptides and nucleic acids — where the sequence, not the wording, is what has to be searched.

Why Run a Biological Sequence Search

Compare a new sequence against what is known

To establish how a newly created sequence compares with known sequences, using BLAST alignment regions — which helps determine whether the invention involves a biomarker, a GMO, an antibody and so on.

Support modified and recombinant products

To make it possible to produce artificially modified or recombinant proteins and nucleic acids — DNA, RNA, enzymes, hormones, peptides.

Before launch or scale-up (FTO)

Before launching a product or scaling up, a sequence search establishes whether target genes or proteins have already been claimed, by searching and evaluating granted patents that use the sequences of interest.

Enforceability checks and litigation

It helps establish whether a claimed sequence is known in the prior art, or was arrived at using obvious earlier-known sequences — the question that decides enforceability checks and infringement cases.

Before licensing or collaborating

Worth running before you license an innovation or enter a collaboration around it.

Early-stage and prototype work

Sequence searching can be significant while the product is still at an early or prototype phase, when there is still room to change direction.

Who It Is For

  • R&D organisations and centres working on novel strains, genetically modified foods, therapeutic targets or antibody development.
  • Technology transfer offices, universities and colleges.
  • Individual inventors.
  • Parties to infringement cases — plaintiffs, defendants and law firms.
  • IP consultants.
  • Primary researchers and computational scientists working in dry labs or bioinformatics.

Why Consider Synoptic IP

Searchers who know how sequence claims are written

Our sequence searchers are well versed in how patent claims reference biological sequences — as sub-sequences, precise sequences, homology percentages, super sequences and so on.

Query and database selection done carefully

Our searchers take time establishing the query sequence and choosing which databases to search. That keeps costs down, particularly where multiple sequences are involved, while still giving the coverage needed.

In-house scripts to combine and filter results

Our internal R and MATLAB scripts combine and filter results from databases such as STN, which reduces expense and increases accuracy.

Automatic OCR correction and alignment

Further scripts automatically correct OCR data for sequences and perform alignment to measure homology percentage — particularly useful in FTO searches.

Broad database access

We have access to numerous free and paid databases — STN, Orbit, Derwent Innovation, GenomeQuest — with extensive coverage and full text across jurisdictions, supporting specialised and supplementary searches.

Reports you can actually read

The report covers sequence alignment, identity percentage, coverage and sequence location, laid out to be read rather than decoded.

Full cost transparency

We provide the actual search transcripts, so you can see exactly what was run and what it cost.

We can work on your subscription

Where you would rather searches ran on your own database subscription, we are happy to work that way.

Client Testimonials

Words From Our Clients

Verified LinkedIn reviews and client correspondence from patent attorneys and in-house IP teams who come back to us project after project.

★★★★★

We were very pleased with the patentability and FTO report that you produced for us back in November 2024.

FBClient ContactFrontierBio · Client since 2024
Client email · Name withheld
★★★★★

I used Synoptic for a validity search and was pleased with the results. The rates were highly competitive, the deliverable was on time, and the results were as good as (if not better than) other searches I’ve used.

Erin J. FoxErin J. FoxIntellectual Property Counsel · ITW
LinkedIn review · Public & verified
★★★★★

Thank you — the search was quite helpful. We’ll have your invoice processed promptly.

QBPatent AttorneyQuarles & Brady · Client since 2018
Client email · Name withheld
★★★★★

Thank you for your work on this matter. We were pleased with the search and will consider you for future searches.

MGPatent AttorneyMerchant & Gould · Client since 2018
Client email · Name withheld

Looking for a First-Class Patent Search Consultant?

Get Quotes Now!

Biological Sequence Search

Synoptic IP’s comprehensive Biological Sequence Search is made to uncover even the most complex sequences that are buried deep inside a wide range of patent and non-patent literature, making it the perfect tool for Fortune 500 companies and famous research laboratories creating antibodies, primers, and therapeutics like peptides and nucleic acids.

[wpb-pcf-button]

Why Perform a Biological Sequence Search with Results?

Biological Sequence Search via Synoptic IP is useful for:

Why Synoptic IP?

Read More on Our Blogs

Explore more on our blogs to have a better understanding of our services.

IP Strategy blog placeholder image

The Next Wave of Neuromodulation

Neuromodulation used to be a quiet corner of medtech — a handful of chronic-pain and movement-disorder devices, slow-moving and predictable. That is no longer true, and the patent landscape shows exactly where the next generation of advantage is being built.

Read Full Article
IP Strategy blog placeholder image

A Guide to Markush Structure Patent Search and Analysis

Imagine a picture representing not just a single molecule, but an entire family of related compound markush structure search. This is the essence of the Markush structure. It uses variables and wildcards to include a diverse set of molecules that share a common core structure.

Read Full Article