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—  Prior Art Search & Analysis

Chemical Structure Search

Identify chemical structures cited in both patent and non-patent publications — drawn as complete structures, as variations in functional moieties, or as chains.

  • 4,000+projects delivered
  • 70+clients
  • 12+years in practice
  • 6 yrsaverage engineer experience

In chemistry, biochemistry and pharmaceuticals this is often the only reliable way to find the most pertinent references for an invention. It lets you advance R&D, influence ongoing patent litigation, monitor the competition and strengthen your intellectual property position. The service is aimed at the pharmaceutical and chemical sectors: it helps R&D professionals in their search for innovation, lets researchers work from a fuller picture, and gives IP counsel what they need to safeguard their clients’ rights.

When to Run a Systematic Structure Search

Compounds text searching will not find

To identify pertinent chemical compounds whose common name or IUPAC name never appears in the references.

Pinpoint results from the Markush structure

To identify results precisely from the Markush structure of the molecule, and from there find the applicable patents.

Strengthen a wider search

To improve landscape analysis, freedom-to-operate, patentability and invalidity searches wherever chemistry is involved.

Why Consider Synoptic IP

More than 2,000 structure searches a year

We carry out over 2,000 chemical structure searches annually, so the workflow and the query craft are well practised.

Technical grasp of complex structures

Our team has the technical proficiency to interpret complex structures, which is where the judgement in this work actually lives.

Skilled at structured queries

We are practised at building structured queries and getting good results out of structure search databases.

Substitutes and broader structures considered

Our analysis identifies structural similarities with substitutes, and weighs the option of choosing a solution with a broader structure.

API, substances, processes and polymers

We search for active pharmaceutical ingredients (API), chemical substances, chemical processes and polymers.

Multiple levels of quality check

Every search passes through several rounds of quality checking before delivery.

Cost matched to structure complexity

We adjust the search cost to the complexity of the chemical structure rather than charging a flat rate regardless.

Client Testimonials

Words From Our Clients

Verified LinkedIn reviews and client correspondence from patent attorneys and in-house IP teams who come back to us project after project.

LinkedIn review
★★★★★

I used Synoptic for a validity search and was pleased with the results. The rates were highly competitive, the deliverable was on time, and the results were as good as (if not better than) other searches I’ve used.

Erin J. FoxErin J. FoxIntellectual Property Counsel · ITWPublic & verified
LinkedIn review
★★★★★

Ankit did a very thorough and professional job on a claim chart assignment for us. He showed great perseverance when things got difficult and was able to get the job done. I would work with him again.

Eric BrownEric BrownIP Consultant · Building Viable Licensing ProgramsPublic & verified
Client email
★★★★★

Thank you — the search was quite helpful. We’ll have your invoice processed promptly.

Patent AttorneyQuarles & Brady · Client since 2018Name withheld
Client email
★★★★★

Thank you for your work on this matter. We were pleased with the search and will consider you for future searches.

Patent AttorneyMerchant & Gould · Client since 2018Name withheld
Client email
★★★★★

We were very pleased with the patentability and FTO report that you produced for us back in November 2024.

Client ContactFrontierBio · Client since 2024Name withheld

Frequently Asked Questions

What is a chemical structure search?

A chemical structure search locates chemical data and structures cited in both patent and non-patent material, working from the structure itself rather than from names.

How is a chemical structure search carried out?

Using either paid or free databases. STN is one of the most widely used subscription databases for structure searching; well-known free options include ChemSpider, ChemDraw, SureChEMBL and PubChem.

Why does this search matter?

In chemistry, biochemistry and pharmaceuticals it is essential for finding the most pertinent references for a discovery — which is what lets you strengthen IP rights, drive R&D and keep an eye on the competition.

Who should run one?

Anyone creating a novel chemical entity for therapeutic, diagnostic or research purposes who intends to patent the structure. That includes R&D teams at pharmaceutical companies and researchers across the pharma and chemical fields.

How much does it cost?

Structure searches typically run on specialised subscription databases such as STN, which charge per query executed. The cost therefore varies with the scale of the search and the number of hits to be analysed.

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Ankit Saxena, Head of Hi-Tech Patent Research at Synoptic IP
Reviewed ByAnkit Saxena Head of Hi-Tech Patent Research

Founder of Synoptic IP with 15 years in prior art research and patent analysis. Ankit reviews the search methodology behind this service.

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