—  Prior Art Search & Analysis

Markush Structure Search

A Markush search starts as a chemical structure search and goes further — finding documents with extensive coverage of functional moieties.

That lets you streamline research and development effort, influence ongoing patent litigation, monitor the competition, and strengthen your own intellectual property position.

When to Run a Focused Markush Search

Compounds that text searching will miss

To find important chemical compounds whose common names or IUPAC names never appear in the references — the case where keyword searching quietly fails.

Identify related patents from the structure

To identify related patents on the basis of the molecular Markush structure results rather than nomenclature.

Strengthen another search you are already running

To enhance landscape analysis, freedom-to-operate, patentability and invalidity searches where chemistry is involved.

Why Consider Synoptic IP

More than 1,200 chemical structure searches a year

We run over 1,200 chemical structure searches annually, so the workflow is well established rather than assembled per project.

Comprehensive analysis on paid databases

The analysis is carried out on subscription databases such as STN, not only on what happens to be free.

Experienced structure chemists

Our team includes professionals skilled in interpreting complex chemical structures, which is where most of the judgement in this work sits.

Reports with the detail you need

Reports come with the pertinent information — detected chemical structures, suitable substitutions, coverage information and the rest.

Multiple levels of quality check

Every search passes through multiple-level quality checks before it reaches you.

Free-database structural information too

We also supply structural information available from free sources, including CAS numbers and related specifics.

Client Testimonials

Words From Our Clients

Verified LinkedIn reviews and client correspondence from patent attorneys and in-house IP teams who come back to us project after project.

★★★★★

We were very pleased with the patentability and FTO report that you produced for us back in November 2024.

FBClient ContactFrontierBio · Client since 2024
Client email · Name withheld
★★★★★

I used Synoptic for a validity search and was pleased with the results. The rates were highly competitive, the deliverable was on time, and the results were as good as (if not better than) other searches I’ve used.

Erin J. FoxErin J. FoxIntellectual Property Counsel · ITW
LinkedIn review · Public & verified
★★★★★

Thank you — the search was quite helpful. We’ll have your invoice processed promptly.

QBPatent AttorneyQuarles & Brady · Client since 2018
Client email · Name withheld
★★★★★

Thank you for your work on this matter. We were pleased with the search and will consider you for future searches.

MGPatent AttorneyMerchant & Gould · Client since 2018
Client email · Name withheld

Looking for a First-Class Patent Search Consultant?

Get Quotes Now!

Markush Structure Search

Synoptic IP offers Chemical Structure Search and Analysis, which is a subset of the Markush Structure Search. It starts as a chemical structure search and involves a thorough strategy that enables you to find documents that have extensive coverage for functional moieties, enabling you to streamline research and development efforts, have an impact on ongoing patent litigation, monitor competition, and fortify your intellectual property rights.

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Conduct a focused Markush Structures search:

Why Synoptic IP?

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Imagine a picture representing not just a single molecule, but an entire family of related compound markush structure search. This is the essence of the Markush structure. It uses variables and wildcards to include a diverse set of molecules that share a common core structure.

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